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Flutamide

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Item Details

Product Description

Basic information of Flutamide:

Name

Flutamide

Alias

TIMTEC-BB SBB006930; N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE;2-METHYL-N-(4-NITRO-3-[TRIFLUOROMETHYL]PHENYL)PROPANAMIDE;FLUTAMIDE;AURORA KA-860;2-methyl-4’-nitro-alpha,alpha,alpha-triflouro-m-propionotoluidid;2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)-propanamid

CAS NO.

13311-84-7

Molecular Formula

C11H11F3N2O3

Molecular Weight

276.21

Quality Standard

EP/USP

Package Size

1kg/drum;25kg/drum or per customer's requirements

Use of Flutamide:

Flutamide is a nonsteroidal antiandrogen drug; antineoplastic (hormonal).

COA ofFlutamide :

Tests Carried Out

Limits

Observation

Characteristics

Pale yellow crystalline powder

Pale yellow crystalline powder

Identification

Meets the requirements

Meets the requirements

Melting Point

110-114°C( does not exceed 2°C)

111.5-112.0°C

Loss on Drying

Not more than 0.5%

0.3%

Residue on ignition

Not more than 0.1%

0.08%

Relative Substance

4-Nitro-3-trifluoroethylacetanilide:

NMT: 0.2%

0.09%

4-Nitro-3-trifluoromethylaniline:

NMT: 0.15%

Not detected

3-trifluoromethylaniline:

NMT: 0.2%

0.02%

4-Nitro-3-trifluoromethylpropionanilide:NMT: 0.3%

Not detected

3-trifluoromethylisobutyranilide:

NMT: 0.2%

Not detected

o-Flutamide:NMT: 0.2%

Not detected

Unknown(relative response:1.0):

NMT: 0.05%

Not detected

Total unknown:NMT: 0.1%

Not detected

Total impurities:NMT: 0.4%

0.11%

Solubility

Freely soluble in acetone ethyl acetate soluble in chloroform other practically insoluble mineral oil.petroleumether and water

Meets the requirements

Heavy Metals

Not more than10ppm

Not detected

Content

98.0-101.0%(calculated on the dried basis)

100.3%

Conclusion :Complies with USP30




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