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Ritonavir powder CAS: 155213-67-5

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Item Details

Product Description

1.    Product Information 

Product Name: Ritonavir

Chemical Name: 1,3-thiazol-5-ylmethyl n-[(2s,3s,5r)-3-hydroxy-5-[[(2s)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenyl-hexan-2-yl]carbamate

Cas No.: 155213-67-5

Molecular Formula: C37H48N6O5S2 
Molecular Weight:  720.96 


2. Uses

The main usage Ritonavir is to treat patients with human immunodeficiency virus (HIV), specifically Type 1, the more dangerous and prevalent type of HIV. Usually, Ritonavir and Lopinavir are combined in a tablet or in a liquid solution to make the treatment more effective. Basically, lopinavir and ritonavir act as an antivirus, preventing and reducing the production of HIV virus in the body. Patients should be informed that lopinavir and ritonavir are not used as a cure for HIV; rather, they are only used to treat and manage the condition. The combined drugs also do not prevent the virus from being transmitted from one person to another.

4. Specification

ITEMS

SPECIFICATIONS   (USP)

APPEARANCE

WHITE TO ALMOST   WHITE POWDER

SOLUBILITY

FREELY SOLUBLE IN   METHANOL AND IN METHYLENE CHLORIDE; VERY SLIGHTLY SOLUBLE IN ACETONITRILE;   PRACTICALLY INSOLUBLE IN WATER

IDENTIFICATION

A)      BY IR THE INFRA RED ABSORPTION SPECTRUM OF   THE SAMPLE IS CONCORDANT WITH THAT OF A SIMILAR PREPARATION OF RITONAVIR   WORKING STANDARD/USP RS.

B)      BY HPLC: THE RETENTION TIME OF THE MAJOR   PEAK IN THE CHROMATOGRAM OF THE ASSAY PREPARATION CORRESPONDS TO THAT IN THE   CHROMATOGRAM OF THE STANDARD PREPARATION AS OBTAINED IN THE ASSAY.

C)      X-RAY DIFFRACTION: THE X-RAY DIFFRACTION   PATTERN CONFORMS TO THAT OF USP RITONAVIR RS.

HEAVY METALS

NMT 0.002%

WATER

NMT 0.5%

RESIDUE ON IGNITION

NOT MORE THAN 0.1%

RELATED COMPOUNDS

IMPURITY A + B=0.10%

IMPURITY C=0.10%

IMPURITY D=0.10%

IMPURITY E=0.15%

IMPURITY F=0.10%

IMPURITY G=0.10%

IMPURITY H=0.10%

IMPURITY I=0.10%

IMPURITY J+K=0.10%


IMPURITY L=0.10%

IMPURITY M=0.10%

IMPURITY N=0.10%

IMPURITY O=0.15%

IMPURITY P=0.10%

IMPURITY Q=0.10%

IMPURITY R=0.10%

IMPURITY S=0.10%

IMPURITY T=0.15%

IMPURITY U=0.10%

ANY UNSPECIFIED  IMPURITY =0.10%

TOTAL IMPUTITIES =0.60%

ASSSAY 

98.0% TO 102.0% ON ANHYDROUS BASIS

RESIDUAL SOLVENTS

ETHYL ACETATE: NMT 0.5%

TETRAHYDROFURAN :NMT 0.05%

N-HEPTANE:NMT 0.15% 


5. Specifications

Fast Delivery  
Professional Manufacturer  
ISO, USP standard
Good Quality and reasonable price


Specializing in the research, development and custom manufacturing of ritonavir cas:155213-67-5, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.

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